Vaccine Against Allergies Become A Reality

 

Molecular surface of Immunoglobulin (IgG) Mole...

Molecular surface of Immunoglobulin (IgG)

 

The prevalence of allergic diseases is global and growing. Allergic diseases are becoming epidemic. Food allergy sufferers double in the last ten years. The latest study – using current trends of data- estimates that half of all Europeans will suffer from allergy by 2015. Allergy has no cure recently. The treatment is whether suppress the symptoms or lessen the inflammation using drugs, antihistamines, and steroids. This huge anti-allergy drug market anticipates to exceed $14.7 billion by 2015 in the U.S. Allergy vaccine sales were exceed $642 million worldwide in 2010.

When your body is exposed to an allergen it triggers an antigen-specific antibody, Immunoglobulin E (IgE) formation in the blood. This molecule undergo on a cellular process known as degranulation which encourage white blood cells (WBC) to release histamine, which causes all the allergic symptoms like hay fever, watery eyes, runny nose. Just suppressing these allergic symptoms doesn’t put an end to the problem.

Scientists in Finland, used a modern molecular biotechnology, discovered unique IgE-binding structures in allergens which can be genetically modified so they do not able to bind IgE anymore but they still stimulate the formation of Immunoglobulin G (IgG).  IgG is a friendly cuisine of IgE. IgG protects you from allergic symptoms by stopping the formation of IgE allergen complexes. That could block the degranulation and histamin release from white blood cells and thus block that irritating symptoms.

In that way the body develops a natural immunity against each allergy they have been vaccinated for.

Scientists at the University of Eastern Finland led by Professor Juhu Rouvinen, in cooperation with Professors Kristiina Takkinen and Hans Söderlun from VTT, a technical research center in Finland, discovered a vaccine that saved millions. The team established a new bio-tech company called Desentum to have the vaccine on the market within five to seven years.

The vaccine has a strong demand on the market. 65 million people in the U.S. and 87 million in Europe have some kind of allergy. Millions of people waiting for hope to escape from their misery.

Source:
           www.forbes.com
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